News

Sciences Animales Paris-Saclay
Article

14 September 2023

Redaction: GABI - Edition P. Huan

The composition of the caecal microbiota of laying hens infected with IBV varies according to genetic lineage and vaccination status

Vaccination of livestock is one of the most effective ways to prevent infectious diseases. The links between vaccine response and variations in the gut microbiota are poorly studied, yet the latter plays a considerable role in the regulation of immunity. In addition, it has been established that genetic variations in hens can influence the composition of the microbiota and the vaccine response.
Article

02 November 2023

Redaction: SAPS - Edition P. Huan

18e European Placenta Group (EPG), November 23rd - 25th, INRAE Jouy-en-Josas

The 18th European Placenta Group (EPG) meeting will take place both online and in person in Jouy en Josas, France, jointly as a regional meeting for the International Federation of Placental Associations. EPG gathers scientists working on all aspects of mammalian placentas, in humans and animals.
Article

02 November 2023

Redaction: SAPS- Edition P. Huan - translation W. Brand-Wiliams

Predicting male fertility from sperm methylomes: application to 120 bulls with hundreds of artificial insemination records

Conflicting results regarding alterations to sperm DNA methylation in cases of spermatogenesis defects, male infertility and poor developmental outcomes have been reported in humans. Bulls used for artificial insemination represent a relevant model in this field, as the broad dissemination of bull semen considerably alleviates confounding factors and enables the precise assessment of male fertility. This study was therefore designed to assess the potential for sperm DNA methylation to predict bull fertility.
Heatmap d'expression des clonotypes les plus partagés chez les poissons immunisés
Article

02 November 2023

Redaction: SAPS - Edition P. Huan - Tranlations W. Brand-Williams

Comparison of clonotypic IgH repertoires in the pronephros and spleen of a Teleost fish upon sytemic viral infection

In fish that are deprived of lymph nodes, the kinetics and location of B responses are poorly characterized. The pronephros is the site of differentiation of B cells and the niche where plasmocytes persist. In a study implicating several partners that was published in the Journal of Immunology, scientists from the Molecular Virology and Immunology Unit – VIM (INRAE/UVSQ/UPSaclay, Jouy-en-Josas) analyzed the IgHμ repertoire of rainbow trout in this tissue after primary immunization and a boost with viral hemorrhagic septicemia virus (VHSV).
Article

02 November 2023

Redaction: SAPS - Edition P. Huan

Assessment of the Safety and Efficacy of an Oral Probiotic-Based Vaccine Against Aspergillus Infection in Captive-Bred Humboldt Penguins (Spheniscus humboldti)

Aspergillosis is a major cause of morbidity and mortality in captive-bred penguin species. Currently, there is no registered vaccine to prevent aspergillosis. In this study, a collaborative group including veterinarians of the Beauval Zoo and researchers of the UMR-BIPAR found that Escherichia coli Nissle represents a safe potential probiotic-based vaccine with a protective effect against aspergillosis in Humboldt penguins that deserves to be further explored for therapeutic uses in these animals.
INRAE
Article

14 September 2023

Redaction: INRAE - Edition P. Huan

Tenure-Track Junior Professor Chairs : Two job offers to join the SAPS units

This contract is intended for scientists with a PhD who have already demonstrated their ability to produce excellent research. It offers the opportunity, after a three-year pre-tenure period and an evaluation, to be granted tenure in the corps of research directors (DR2). Registration is open until April 21, 2023.
Sciences Animales Paris-Saclay
Article

14 September 2023

Redaction: SAPS - Edition P. Huan - Translation W. Brand-Williams

How can the analysis of the genome change how patients with azoospermia are managed?

This study which was published in Human Reproduction evaluated the relevancy of Whole Exome Sequencing (WES) in patients for which a first testicuar biopsy was performed, showing a homogenous blocage of sperm maturation during prophase I of meiosis.
Article

14 September 2023

Redaction: SAPS- Edition P. Huan - Translation W. Brand-Williams

The MoSAR unit has a PhD position available (with financing, beginning in October 2022)

The subject is : "DigitWelfare: a hybrid approach to modelling to characterize the activity profile of dairy goats in relation with welfare."
@INRAE Delphine Rousseau-Ralliard Légende : A summary of the feto-placental effects of maternal exposition to a high-gat diet  either during preconceptional or gestational periods
Article

14 September 2023

Redaction: UMR BREED - Edition P. Huan - Translation W. Brand-Williams

High-fat maternal diet affects offspring phenotype: importance of windows of exposure

Being overweight or obese, in association with a high-fat diet is a major problem for public health, especially in women of childbearing age. We showed that in the rabbit, a high-fat maternal diet (H) administered at puberty and during gestation, affects the embryo development at the blastocyst stage, inducing intra-uterine growth retardation and placental metabolic sex-specific adaptations, without allowing to discriminate the effect of preconceptual exposition from that of gestational exposition.
Sciences Animales Paris-Saclay
Article

14 September 2023

Redaction: BREED - Edition P. Huan - Translation W. Brand-Williams

Chromatin transcription and reorganisation go hand in hand

We showed that ribosomal genes (rDNA) are organized in a unique manner in the embryo (very differently than somatic cells) between the 4-cell and 16-cell stages and that this organization depends on their transcription state. We also showed that they could participate in the establishment of an environment that is favorable for the transcription of major satellite sequences - repeated sequences that are normally silent since they are located on the peri-centromeric heterochromatin.
@INRAE Emilie Derisoud
Article

02 November 2023

Redaction: UMR BREED - Edition P. Huan

Estimation of milk production in lactating mares and factors influencing milk yield

Research on mare milk is mainly concentrated on quality and information on quantity is incomplete, mainly since there has been no consensus on a method for milk yield measurement. Live weight, body condition during foaling and the age of mares are factors that influence mare milk production. The influence of the parity of the mare, however, remains unclear.
Sciences Animales Paris-Saclay
Article

14 September 2023

Redaction: UMR BIPAR - Edition SAPS P. Huan

Anti-microbiota vaccine reduces avian malaria infection within mosquito vectors

In this study, we showed that anti-microbiota vaccination in birds targeting Enterobacteriaceae bacteria within mosquito midguts modulates the mosquito microbiota and disrupt Plasmodium relictum development in its natural vector Culex quinquefasciatus. This study is the first proof of concept that anti-microbiota vaccines can be used as a novel tool to control malaria transmission and potentially other vector-borne pathogens.
Article

02 November 2023

Redaction: GABI - Edition P. Huan - Translation W. Brand-Williams

The H2020 project GEroNIMO launches a hackathon

The GEroNIMO project is organizing a hackathon on the contribution of new genomic technologies (NGT) to the sustainable and efficient production of pigs and chickens with high biodiversity and good animal welfare. ARE YOU A STUDENT? PARTICIPATE!
@INRAE D. Boichard
Article

02 November 2023

Redaction: GABI - Edition P. Huan Translation W. Brand-Williams

Publication of dairy catlle indexes estimated with the "Single Step" method

Single Step is a genomic evaluation method that simultaneously uses all animals, whether genotyped or not, in only one step. It is a major evolution for genomic selection. This important work was done in three steps: an entirely new software was developed by INRAE (HSSGBLUP); validating studies and a comparison was done by the UMT eBIS (ASAP project); and deployment work as part of a UNIGENO project coordinated by GenEval and Idele.
Article

02 November 2023

Redaction: INRAE - Edition P. Huan - Translation W Brand-Williams

The CiTiQUE programme is awarded the prize for Citizen Science in the "crowdsourcing" category

During the International Agriculture Fair in 2022, INRAE unveiled the winners of the first edition of its Community Science Awards, the principle of which was adopted in the research programming law.
Article

02 November 2023

Redaction: SAPS - Edition P. Huan - Translation W. Brand-Williams

Seven steps to improve open science practices in animal science

The open science movement aims to ensure accessibility, reproducibility and transparency of research. However, the adoption of open science practices in animal science is still in its infancy. To move forward in this area, we propose here seven practical steps to adopt open science in animal science. We hope that this paper will help move the research practices of animal scientists toward open, reproducible, and transparent science, thereby enabling the field to gain public trust and meet future challenges to ensure reliable research. Although this paper is primarily directed at animal science researchers, the steps discussed here are also applicable to other research areas.
Sciences Animales Paris-Saclay
Article

14 September 2023

Redaction: GABI - Edition P. Huan

Laser microdissection allows fine in situ analysis of the interaction between extracellular bacteria and the host

La microdissection laser : un outil pour analyser l’expression in situ des gènes de l'entérobactérie Bacillus cereus lors de la colonisation intestinale de l’hôte Galleria mellonella.
Article

14 September 2023

Redaction: SAPS- Edition P. Huan

The BREED unit has a PhD position available (with financing, beginning in Octobre, 2022)

The subject is: "Induction of dormancy in pluripotent cells and mammal embryos."